Senior Manager, Vector Biology Job at 6084-Janssen Research & Development Legal Entity, Cambridge, MA

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  • 6084-Janssen Research & Development Legal Entity
  • Cambridge, MA

Job Description

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

People Leader

All Job Posting Locations:

Cambridge Massachusetts United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Senior Manager Vector Biology to be in Cambridge MA.

Purpose:

We are seeking an experienced Senior Manager to oversee a multidisciplinary team responsible for advancing viral vector biology vector design improvements assay development and optimization of lentiviral vectors for in vivo cell this role you will provide technical leadership and strategic direction to drive the teams research and development efforts with a focus on enhancing cell-specific transduction capabilities.

You will be responsible for:

  • Manage a team of scientists and engineers focused on viral vector biology vector design and assay development

  • Oversee the teams work to improve lentiviral vector design and performance for in vivo cell targeting including:

    • Identifying optimal target molecules and cell surface receptors for efficient vector binding and entry

    • Leveraging expertise in cell biology to understand and enhance vector-cell interactions for improved cell type-specific transduction

    • Designing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency

  • Develop and implement strategies to optimize lentiviral vectors for specific cell type transduction

  • Ensure the team designs and validates robust assays to test key assumptions about vector biology cell targeting and overall performance

  • Collaborate cross-functionally with other R&D teams to integrate vector innovations into cell and gene therapy programs

  • Provide technical leadership and strategic direction to drive the teams research and development efforts

  • Manage budgets timelines and resources to deliver on team objectives

  • Foster a culture of innovation continuous improvement and strong scientific rigor

Qualifications:

  • Advanced degree (PhD preferred) in molecular biology virology bioengineering or a related field with 6-8 years of relevant industry experience in cell and gene therapy with a strong background in viral vector development

  • Deep expertise in lentiviral vector biology design and optimization for in vivo applications including strong knowledge of cell biology principles to enable efficient cell targeting

  • Extensive experience developing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency

  • Demonstrated track record of leveraging cell biology insights to engineer improved cell-targeting capabilities of viral vectors

  • Thorough understanding of cell surface receptor biology cell signaling pathways and intracellular trafficking mechanisms to inform vector design and optimization

  • Proven track record of leading multidisciplinary teams and delivering tangible R&D outcomes

  • Excellent problem-solving project management and communication skills

  • Ability to translate complex scientific concepts including cell biology into actionable strategies

  • Strong collaborative mindset and ability to work effectively cross-functionally

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

Required Skills:

Preferred Skills:

Big Data Management Data Reporting Data Savvy Developing Others Drug Discovery Development Good Clinical Practice (GCP) Inclusive Leadership Industry Analysis Leadership Molecular Diagnostics Operational Excellence Pharmaceutical Microbiology Product Knowledge Project Reporting Scientific Research Strategic Thinking Sustainability Team Management

The anticipated base pay range for this position is :

$137000.00 - $235750.00

Additional Description for Pay Transparency:

Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).

Subject to the terms of their respective policies and date of hire employees are eligible for the following time off benefits:
Vacation 120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado 48 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year
Holiday pay including Floating Holidays 13 days per calendar year
Work Personal and Family Time - up to 40 hours per calendar year
Parental Leave 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave 80 hours in a 52-week rolling period10 days
Volunteer Leave 32 hours per calendar year
Military Spouse Time-Off 80 hours per calendar year

For additional general information on Company benefits please go to: - Experience:

Senior Manager

Job Tags

Full time, Local area, Immediate start

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